6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3-4]pyrrolo[1-3-d]pyridazinone and Glioblastoma

6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3-4]pyrrolo[1-3-d]pyridazinone has been researched along with Glioblastoma* in 1 studies

Other Studies

1 other study(ies) available for 6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3-4]pyrrolo[1-3-d]pyridazinone and Glioblastoma

Article	Year
Identification of Parthenolide Dimers as Activators of Pyruvate Kinase M2 in Xenografts of Glioblastoma Multiforme in Vivo. Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4 Herein we detail the discovery of a series of parthenolide dimers as activators of PKM2 and evaluation of their anti-GBM activities. The most promising compound Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Prodrugs; Protein Kinase Inhibitors; Pyruvate Kinase; Sesquiterpenes; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays	2020

Article

Year

Identification of Parthenolide Dimers as Activators of Pyruvate Kinase M2 in Xenografts of Glioblastoma Multiforme in Vivo.

Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

Herein we detail the discovery of a series of parthenolide dimers as activators of PKM2 and evaluation of their anti-GBM activities. The most promising compound

Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Prodrugs; Protein Kinase Inhibitors; Pyruvate Kinase; Sesquiterpenes; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2020